Rat poisons can be divided into two categories—first generation anticoagulants (FGARS) that work by blocking the manufacture of Vitamin K, which is the blood clotting agent. These include poisons such as Warfarin and coumatetralyl. These generally have shorter elimination half lives and work over days, requiring the rat to eat a lot before they become effective. The rat eats these and dies by bleeding out. Second generation rodenticides (SGARS) which include difenacoum, brodifacoum and bromethalin (Tomcat XI), bromadiolone (D-Con), supposed to kill the rat with a single dose, but these also take time to work, requiring the rat to eat more and accumulate more poison. Dry ice is another measure that has been used in cities like Boston, which works to asphyxiate rats but was stopped there because it was not registered as a pesticide.
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